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O·H+T gallery, founded in 2001 by Kathleen O'Hara and Caroline Taggart, exhibits contemporary work in all media. Offering some of the most distinctive and adventurous current work, the gallery represents both emerging and mid-career artists. The O·H+T gallery space is at the corner of Harrison and Thayer Streets in Boston's South End. This quickly developing neighborhood is home to nine galleries and numerous artist's studios.

Samson Projects, established in March 2004, blends the elements of a commercial gallery with the experimental attitude of an alternative exhibition space. The artists they represent are Nicole Cherubini, SunTek Chung, Taylor Davis, Craig Drennen, Jeffrey Gibson and Rune Olsen. Samson Projects creates and presents programs that explore the diversity of cultures and voices that continually shape contemporary art and ideas today, introducing emerging and under-recognized artists as well as established artists. Their mission is to act as an interdisciplinary laboratory for the convergence of film, video, performance, music, design and visual art. Their goal is to bring the broadest spectrum of contemporary art along with the most exciting new artists to Boston.

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Space 242 is an "alternative" to the fine art galleries throughout the city. This hotspot is truly the epicenter of Boston's emerging underground art scene. Geared to connecting emerging pop surrealists and low-brow artists with new collectors at affordable prices, this new enclave showcases artwork from many mediums including photography, illustration, painting, mixed media and sculpture. Space 242 hosts a monthly opening reception on the last Friday of every month from 6-8 pm.